ESMO 2024 Videos VL

TiNivo-2 Trial Results in Advanced Renal Cell Carcinoma Treatment - Toni Choueiri

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Toni Choueiri discusses the TiNivo-2 trial results, comparing tivozanib-nivolumab combination to tivozanib monotherapy in advanced clear cell renal cell carcinoma. The study, involving 343 patients, shows no benefit in rechallenging with nivolumab after prior immunotherapy. Tivozanib monotherapy demonstrates efficacy, particularly in patients progressing directly from immunotherapy, with a progres...

Genetic Profiles in Early vs. Late Stage Urothelial Cancer - Dag Stormoen

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Dag Stormoen discusses research comparing genetic profiles of early and late-stage urothelial tract cancer. The study finds similar mutational profiles between muscle-invasive bladder cancer and heavily treated metastatic disease. Notably, a small cohort of advanced-stage patients showed unexpectedly long survival, with some living beyond five years. The research highlights the potential of geneti...