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- Ashish Kamat, Ananya Choudhury, and Nick James discuss trimodal therapy, or radiotherapy, for bladder preservation in patients with bladder cancer. Dr. Choudhury touches on how to differentiate treatment between moving towards cystectomy and deciding on radiotherapy. They also discuss differing radiotherapy schedules and how those differences can affect patients. Biographies: Ananya Choudhury, MA,...
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- Fernando Korkes discusses the groundbreaking work of Korkes and his team in Brazil. Addressing the issue of high mortality rates for muscle-invasive bladder cancer in developing countries, Dr. Korkes elaborates on the implementation of a multidisciplinary clinical practice called the CABEM project. The initiative involved a comprehensive team of medical professionals, led by Dr. Korkes and initiat...
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- Ashish Kamat engages Phillip Abbosh to explore cutting-edge research in bladder cancer. Dr. Abbosh highlights the ongoing RETAIN trial, which examines the safety and feasibility of avoiding cystectomy for patients with muscle-invasive bladder cancer who achieve a complete pathologic response post-neoadjuvant chemotherapy. The trial has enrolled 78 subjects and is awaiting mature data. Alongside, D...
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- Ekaterina Laukhtina and Ashish Kamat discuss urethral recurrence after radical cystectomy. Dr. Laukhtina goes into depth on using urethroscopy to diagnose urethral recurrence as well as when urethrectomy may be useful highlighting a systematic review and meta-analysis assessing the incidence and risk factors of urethral recurrence as well as summarizing data on survival outcomes in patients with u...
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- Sophia Kamran joins Sam Chang to discuss her presentation from the GU ASCO 2022 Annual Meeting focusing on novel therapies in bladder cancer and their toxicities, discussing the role of bladder-sparing trimodality therapy with a focus on toxicity and functional outcomes. Biographies: Sophia C. Kamran, MD, Assistant Professor of Radiation Oncology, Harvard Medical School, Massachusetts General Hosp...
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- Carissa Chu joins Sam Chang to discuss data on genetic changes and alterations in urothelial carcinoma. The purpose of the study is to characterize human epidermal growth factor receptor 2 (HER2) (ERBB2) and fibroblast growth factor receptor 3 (FGFR3) mutations in a prospectively collected cohort of urothelial cancers. Dr. Chu highlights the key findings from this study. Biographies: Carissa Chu,...
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- Alicia Morgans is joined by Jeannie Hoffman-Censits and Elizabeth Guancial to discuss the challenges women face navigating a bladder cancer diagnosis. In 2022, the American Cancer Society estimates more than 81,000 will be diagnosed with bladder cancer in the United States. Of those, 61,700 will be men, and 19,480 will be women. Drs. Morgans, Hoffman-Censits, and Guancial discuss the importance of...
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- Ashish Kamat and Peter Black delve into a new term, 'BCG-Exposed', in high-risk non-muscle-invasive bladder cancer. Published by the International Bladder Cancer Group, the definition sheds light on this gray area, aiming to enhance clinical trial design and regulatory processes. Dr. Black's publication explores the intricacies of various disease states associated with BCG (Bacillus Calmette-Guéri...
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- In a discussion hosted by Ashish Kamat, Boris Gershman presents his study comparing radical cystectomy and trimodality therapy for muscle-invasive urothelial carcinoma of the bladder. The study aims to fill a significant knowledge gap, as no randomized trials have directly compared these treatments. Using an emulation framework to replicate the UK's SPARE trial, which closed due to low recruitment...
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- Benjamin Miron, a 2021 recent recipient of the Bladder Cancer Advocacy Network's (BCAN) Young Investigator Award joins Alicia Morgans to speak about the Young Investigator Award Program. Dr. Miron speaks on the importance of this program and the opportunity it provides young investigators to jumpstart their careers. This funding Dr. Miron received helped to investigate new biomarkers for bladder c...
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