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AR Indifferent Subtype Tumors in Prostate Cancer - Ana Aparicio

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Ana Aparicio joins Alicia Morgans at ASCO GU 2020 to discuss her work with AR indifferent tumors in the field of prostate cancer. Among the topics discussed, Dr. Aparicio stressed the importance of understanding clinical features and the development of a profile of this AR indifferent subtype in order to allow for easier identification. The two further discuss the research and ongoing clinical tri...

Quality of Life in the Treatment of mHSPC: The STAMPEDE Trial - Hannah Rush

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Hannah Rush joins Alicia Morgans discussing the quality of life outcomes we have seen from patients receiving docetaxel or abiraterone in the STAMPEDE trial. STAMPEDE is a multi-arm, multi-stage trial investigating various therapeutic strategies for the management of locally advanced or metastatic hormone-naïve prostate cancer. In recent years, both docetaxel and abiraterone have been shown to imp...

Radiotherapy Planning in Prostate Cancer Patients - Matteo Sepulcri and Laura Evangelista

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Matteo Sepulcri and Laura Evangelista present on radiotherapy in prostate cancer patients. Together they touch on subjects such as radiotherapy treatments for prostate cancer and the role of PET/CT in different stages of prostate cancer. This presentation took place as part of the annual Society of Nuclear Medicine and Molecular Imaging (SNMMI) meeting. Biographies: Matteo Sepulcri, Radiation Onco...

Supportive Therapy in Androgen Deprivation (STAND) - Rahul Aggarwal

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Charles Ryan sits down with Rahul Aggarwal to discuss one of the first of its kind, the UCSF STAND (Supportive Therapy in Androgen Deprivation) Clinic providing comprehensive care to men with prostate cancer who are receiving androgen deprivation therapy (ADT). While ADT is extremely effective, it causes side effects, including fatigue, hot flashes, and sexual changes, such as decreased libido (se...

Phase III Nadofaragene Firadenovec for BCG-Unresponsive Non-Muscle Invasive Bladder Cancer - Joshua J. Meeks

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In this discussion, Josh Meeks joins Alicia Morgans to review the new advances phase III Nadofaragene Firadenovec (Adstiladrin®) trial for BCG unresponsive non-muscle invasive bladder cancer patients. Dr. Meeks details the results of this recently presented trial data and why he believes this is the beginning of the next era in treating these patients. Biographies: Josh J. Meeks, MD, Ph.D., Assist...

Updates on Bladder Cancer Clinical Trials ASCO GU 2020 - Matthew Galsky

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Joining Alicia Morgans is Matt Galsky to discuss the biggest updates in bladder cancer clinical trials. Building off of his overview of IMvigor130, KEYNOTE-361, and JAVELIN Bladder 100, Dr. Galsky provides insight on how he incorporates clinical data into his everyday practice and the direction he believes the field is moving towards in the future. Biographies: Matthew Galsky, MD Director of Genit...

Reproducibility and Repeatability of Quantitative FDHT Uptake Metrics in CRPC - Andrew Scott

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Andrew Scott, MD presented a multinational trial looking at a fluorodihydrotestosterone (FDHT) in patients with castration-resistant prostate cancer on behalf of colleagues from a number of institutions. The intent was that they would look at whether or not this was a test which could be reliably introduced in individual patients at multiple centers in multiple continents, and whether or not there...

Research and Clinical Practice Strategies Due to the BCG Shortage - Sam S. Chang

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Sam Chang joins Ashish Kamat to discuss strategies for clinical trials and patient selection required in the face of the world-wide shortage of BCG. Biographies: Sam S. Chang, MD, MBA , Patricia and Rodes Hart Endowed Chair of Urologic Surgery Professor Department of Urology at Vanderbilt University Medical Center, Department of Urology Ashish Kamat, MD, MBBS Professor of Urology and Wayne B. Dudd...

Bladder Cancer Research That Impacts Urology Clinical Practice - Josh Meeks

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Joshua Meeks joins Ashish Kamat in discussing the most recent relevant research papers in bladder cancer. Together they explore the publications on checkpoint inhibitors, the use of The Cancer Genome Atlas, Enhanced Recovery after Cystectomy and the impact of blue light flexible cystoscopy with CYSVIEW. Biographies: Josh J. Meeks, MD, Ph.D., Assistant Professor of Urology and Biochemistry and Mole...

Implementing Prostate Cancer Working Group 3 Criteria in Clinical Trials- Michael Morris and Lawrence Schwartz

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Alicia Morgans welcomes Michael Morris and Lawrence Schwartz to discuss the Prostate Cancer Working Group criteria as a refresher for investigators who are treating men with prostate cancer in clinical trials. Biographies: Michael J. Morris, MD., is the Clinical Director, Genitourinary Medical Oncology Service & Prostate Cancer Section Head, Division of Solid Tumor Oncology, Memorial Sloan Ketteri...