- Details
- Sam Chang host Mario de Angelis to discuss a study on trimodal therapy (TMT) for urothelial and non-urothelial invasive bladder cancer. Dr. De Angelis presents findings from a SEER database analysis of over 5,000 patients treated with TMT. The study reveals that TMT use has increased for organ-confined urothelial carcinoma but decreased for non-urothelial cases. For organ-confined disease, patient...
|
- Details
- Ruchika Talwar host Nirmish Singla to discuss a study on testicular cancer outcomes in Hispanic men. Dr. Singla presents findings from a SEER registry analysis spanning 20 years, revealing that Hispanic patients are more likely to be diagnosed at a younger age but with more aggressive disease characteristics. The study shows lower cancer-specific survival for Hispanics with non-seminoma across all...
|
- Details
- Andrea Miyahira interviews Michael Haffner about his group's study on the expression of TROP2, CEACAM5, and DLL3 in metastatic prostate cancer, published in NEJM Evidence. Dr. Haffner discusses their analysis of over 750 samples from 52 patients in a rapid autopsy cohort, examining protein expression across different molecular subtypes of castration-resistant prostate cancer. The study reveals dis...
|
- Details
- Sam Chang host Paul Crispen to discuss his study on BCG efficacy in patients with upper tract urothelial carcinoma following nephroureterectomy. Dr. Crispen discusses the findings, which show that patients with a history of upper tract disease experience bladder tumor recurrences sooner than those with primary bladder tumors, despite similar overall recurrence rates. The study reveals a higher ris...
|
- Details
- Lymphocytes are closely linked to mechanisms of action of immuno-oncology (IO) agents. We aimed to assess the prognostic significance of absolute lymphocyte count (ALC) in patients with metastatic renal cell carcinoma (mRCC). Biographies: Kosuke Takemura, MD, PhD, MPH, Staff Urologist, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan Related Content: Prognostic Sign...
|
- Details
- Therapeutic options for patients with non-muscle-invasive bladder cancer (NMIBC) have traditionally been limited to intravesical immunotherapy or chemotherapy. A considerable number of new options have been investigated in recent years. Our aim was to review the efficacy and toxicity of novel therapeutic options (results already reported or currently under investigation) for patients with NMIBC. B...
|
- Details
- Ruchika Talwar interviews Eric Walton and Akanksha Metha about their study on the impact of legislation on access to gender-affirming care, published in the Gold Journal. The research examines the effects of the Affordable Care Act on insurance coverage for transgender and gender-diverse adults using the MarketScan Commercial Claims database from 2009 to 2022. The study reveals a significant incre...
|
- Details
- Ruchika Talwar interviews Kristian Stensland about his publication in Urology Practice on the size and scope of urologic oncology clinical trials. Dr. Stensland discusses their analysis of trials registered on clinicaltrials.gov since 2007, revealing that over 100 patients enroll daily in urologic oncology trials, totaling about 28,000 participants annually. Despite this significant number, enroll...
|
- Details
- Rashid Sayyid and Zachary Klaassen discuss the 2024 updates to the NCCN guidelines for metastatic castration-resistant prostate cancer (mCRPC) treatment. They review the current management algorithm, emphasizing the importance of confirming castrate status and proper staging. The presentation covers treatment options for adenocarcinoma and small cell/neuroendocrine variants, highlighting the signi...
|
- Details
- Anticholinergic medications have long been mainstays of overactive bladder (OAB) treatment. Oxybutynin, a first-generation anticholinergic, still accounts for more than half of all OAB medication prescriptions, despite associations with impaired memory and cognition, as well as mounting evidence that it may increase the risk of incident dementia. Biographies: Michael Chancellor, MD, Corewell Healt...
|
