In this follow-up discussion, Badar Mian and E David Crawford delve deeper into the implications of clinical trials comparing transperineal (TP) and transrectal (TR) prostate biopsies. They address key issues such as antibiotic use, patient comfort, and sampling accuracy. Dr. Mian notes that many European centers still use antibiotics for TP biopsies, contrary to claims of antibiotic avoidance. They discuss the increased pain and potential embarrassment associated with TP biopsies, often leading to sedation use. The conversation highlights that the study found no significant difference in detecting anterior tumors between the two methods. Drs. Crawford and Mian emphasize the importance of having both techniques available and tailoring the approach to individual patient needs. They conclude that the study's results challenge the prevailing notion of TP biopsy superiority, suggesting a more balanced approach to biopsy method selection.

Biographies:

Badar Mian, MD, Urologist, Professor of Surgery, Albany Medical Center, Albany, NY

E. David Crawford, MD, Urologist, Professor of Urology, Jack A. Vickers Director of Prostate Cancer Research, University of California San Diego, San Diego Health, San Diego, CA, The University of Colorado Anschutz Medical Campus, Aurora, CO