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- At the CAncer or Not Cancer: Evaluating and Reconsidering GG1 prostate cancer (CANCER-GG1?) Symposium, experts explore several aspects of prostate cancer diagnosis and active surveillance. The group raises questions about the financial toxicity of active surveillance, particularly for underserved populations. They also consider whether high-quality access to care could improve surveillance outcome...
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- Andrea Miyahira interviews Cornelia (Chien-Kuang) Ding about her study on predicting prostate cancer grade reclassification using a deep learning-based grading algorithm. Dr. Ding discusses their evaluation of the AIRAProstate algorithm across two cohorts at Johns Hopkins University. The study reveals that AI-based upgrading of initial biopsies is associated with later grade reclassification in ac...
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- At the CAncer or Not Cancer: Evaluating and Reconsidering GG1 prostate cancer (CANCER-GG1?) Symposium, experts discuss several key issues in prostate cancer management and nomenclature. The group raises questions about the financial toxicity of active surveillance, particularly for underserved populations, and whether high-quality access to care could improve surveillance outcomes. They also consi...
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- Bruce Montgomery discusses the pivotal role of germline testing in cancer predisposition, particularly within the Million Veterans Program. Focusing on prostate cancer, Dr. Montgomery explains that germline testing, which examines inherited DNA, can identify individuals with genetic predispositions to various cancers, including prostate, breast, ovarian, and pancreatic. This testing is crucial for...
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- Alicia Morgans speaks with Zach Klaassen about his research focusing on the intersection of mental health and prostate cancer care in the veterans’ population. Dr. Klaassen shares insights from his extensive study aimed at creating the world's largest prostate cancer mental health database. Initial findings reveal that veterans with mental health issues are less frequently diagnosed with prostate...
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- Rashid Sayyid and Zach Klaassen review the 2024 NCCN Guidelines for managing very low-risk prostate cancer. Dr. Sayyid defines very low-risk prostate cancer using criteria like T1C stage, PSA levels, and biopsy characteristics. The updated guidelines simplify management based on life expectancy: patients with 10 years or more are recommended active surveillance, while those with less are advised o...
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- Anthony Joshua presents the findings of the MAST trial, a decade-long investigation into the use of metformin for men with low-risk prostate cancer under active surveillance. Conducted across 12 Canadian centers, this randomized Phase III study involved 408 men and aimed to determine if metformin could delay cancer progression. Despite earlier promising studies suggesting potential benefits, the t...
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- Neal Shore interviews Nicholaus Ngowi and Blandina Mmbaga about their work in prostate cancer education and screening in Tanzania. Dr. Ngowi discusses a community-based study revealing that many men in Northern Tanzania have poor knowledge about prostate cancer and face barriers such as misconceptions and cost, leading to late-stage diagnoses. The study, funded by grants from the Prostate Cancer F...
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- Alicia Morgans interviews Brian Gonzalez about his talk at ASCO 2024 on behavioral interventions to mitigate the adverse effects of androgen deprivation therapy (ADT) for prostate cancer patients. Dr. Gonzalez explains that cognitive behavioral therapy (CBT) and physical activity interventions are effective in improving side effects like fatigue, sleep issues, and vasomotor symptoms. He highlights...
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- Ruchika Talwar interviews Abhinav Khanna about his work on AI and prostate cancer surgery. Dr. Khanna discusses his team's development of an AI platform that can identify key surgical steps during robotic prostatectomy with high accuracy. By analyzing video footage from minimally invasive surgeries, this technology aims to turn raw surgical video data into a valuable resource for training, quality...
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