High-grade invasive urothelial carcinoma with focal plasmacytoid differentiation successfully treated by transurethral resection followed by chemoradiotherapy - Abstract

Department of Urology, Yokohama City University Graduate School of Medicine Department of Pathology, Yokohama City University Hospital, Yokohama, Kanagawa, Japan.

 

We report a case of high-grade invasive urothelial carcinoma with plasmacytoid differentiation of the urinary bladder. A 75-year-old woman was referred to our hospital because of macroscopic hematuria. Cystoscopy detected a solid pedunculated bladder tumor, and a transurethral resection of the bladder tumor (TUR-Bt) and the image findings showed pT1N0M0 bladder cancer. The histopathological examination revealed the coexistence of a large component of high-grade invasive urothelial carcinoma and a small component of plasmacytoid carcinoma. Following the TUR-Bt, external beam radiotherapy and chemotherapy with gemcitabine and nedaplatin were carried out. The bladder tumor has not recurred for 2 years after the TUR-Bt.

Written by:
Kawahara T, Oshiro H, Sekiguchi Z, Ito H, Makiyama K, Uemura H, Kubota Y.   Are you the author?

Reference: Int J Urol. 2011 Oct 17. Epub ahead of print.
doi: 10.1111/j.1442-2042.2011.02880.x

PubMed Abstract
PMID: 22004222

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