Very late relapses of germ cell tumors (GCTs) are rare.
There are few reports of relapses occurring beyond 20 years of initial treatment. Here we describe a case of a very late relapse of Stage I testicular non-seminomatous germ cell tumor 27 years after orchiectomy. The relapse presented as a retroperitoneal mass in the precaval lymph nodes with negative tumor markers. It was resected and pathology confirmed it as metastatic teratoma. This case emphasizes the importance of lifelong surveillance for patients with GCTs.
Written by:
Arafat W, Albany C, Ulbright TM, Foster R, Einhorn LH. Are you the author?
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Medicine, Division of Hematology and Oncology, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Urology, Indiana University School of Medicine, Indianapolis, IN, USA.
Reference: J Surg Case Rep. 2014 Jun 2;2014(6). pii: rju051.
doi: 10.1093/jscr/rju051
PubMed Abstract
PMID: 24887427
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