Teratoma with malignant transformation is an uncommon, very aggressive germ cell tumor that has undergone transformation of a somatic teratomatous component to a histologic type identical to a somatic malignancy.
We review the clinical presentation, imaging appearances, and prognosis of this entity and highlight its aggressive behavior by reporting on three patients with metastatic testicular nonseminomatous germ cell tumor with histologically proved malignant transformation.
Written by:
Cabral FC, Krajewski KM, Rosenthal MH, Hirsch MS, Howard SA. Are you the author?
Department of Imaging, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Reference: Clin Imaging. 2014 Apr 28. pii: S0899-7071(14)00112-0.
doi: 10.1016/j.clinimag.2014.04.011
PubMed Abstract
PMID: 24908364
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