Most stage I testicular germ cell tumors are curable by orchiectomy alone.
However, some tumors recur and require subsequent treatment. The point for the management of stage I testicular germ cell tumors is how to reduce the recurrence rate by appropriate adjuvant treatment with less adverse events. The strategy for stage I seminoma and stage I nonseminoma is different. The adjuvant treatment options include radiotherapy and 1-2 courses of carboplatin for seminoma and retroperitoneal lymph node dissection (RPLND) and 1-2 courses of bleomycin, etoposide and cisplatin chemotherapy for nonseminoma. This review discusses recent literature on adjuvant treatment and updates the consensus for the management of stage I testicular germ cell tumor.
Written by:
Nakai Y, Nagahara A, Uemura M, Takayama H, Nonomura N. Are you the author?
The Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan.
Reference: Hinyokika Kiyo. 2012 Dec;58(12):715-20.
PubMed Abstract
PMID: 23328172
Article in Japanese.
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