Testicular cancer is the most frequent solid tumor detected in young adult men. Germ cell tumors (GCTs), particularly seminomas, are the most common type of testicular neoplasms seen in that age population. Most publications have reported decreasing incidence of GCTs in patients above forty years of age. Since the biologic activity of seminomas appears similar across ages, recommended management of senior adults involves a multimodal therapy of radical inguinal orchiectomy with radiation or cytotoxic treatment as needed. Attenuating chemotherapy dosages are critical to ensure better tolerability of associated adverse events. Here we report a case series of 2 men older than fifty years of age with metastatic testicular seminoma. We aim to emphasize a rare clinical entity encountered in the senior adult population.
Case reports in urology. 2019 Nov 24*** epublish ***
Rawad Abou Zahr, Khalil Chalhoub, Imad Matta, Sawsan Horani, Zarouhie Bedoyan, Georges El Hachem, Imad Ghantous, Michel Jabbour
Department of Urology, University of Balamand, Saint George Hospital University Medical Center, Beirut 1100 2807, Lebanon., University of Balamand, Faculty of Medicine and Medical Sciences, Beirut 1100 2807, Lebanon., Department of Pathology, University of Balamand, Saint George Hospital University Medical Center, Beirut 1100 2807, Lebanon., Department of Hematology-Oncology, University of Balamand, Saint George Hospital University Medical Center, Beirut 1100 2807, Lebanon.