BERKELEY, CA (UroToday.com) - Our article contains data pertaining to repeat biopsies in the screening of prostate cancer, based on PSA. The study included a large number of patients, which allowed for accurate statistics to be obtained, and it generated 2 main conclusions. The first one shows the low rate of prostate cancer after third prostate biopsy and the second one shows that the time interval between prostate biopsies does not matter for detecting prostate cancer.
We believe that transurethral resection of the prostate (TURP), as an alternative procedure, can provide adequate tissue samples for diagnosing prostate cancer. The operation should be done in patients with LUTS and patients with constant PSA-connected parameters, like PSA density of the transition zone, PSA density, PSA velocity, complex PSA, and free PSA to total PSA ratio. TURP provides the opportunity for radical prostatectomy in patients with prostate cancer on second stage. With respect to repeat biopsies, we believe that performing them within short time intervals is not necessary in patients who have no suspicious data from DRE, and total PSA in the gray zone of the tumor marker. That is why we believe that a two-year time interval between the biopsies does not increase risk of progression of the disease.
Written by:
I. V. Bakardzhiev as part of Beyond the Abstract on UroToday.com. This initiative offers a method of publishing for the professional urology community. Authors are given an opportunity to expand on the circumstances, limitations etc... of their research by referencing the published abstract.
Department of Urology
Medical University
St. George University Hospital
Plovdiv, Bulgaria
Repeat transrectal prostate biopsies in diagnosing prostate cancer - Abstract
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