Current Role of PET CT in Staging and Management of Penile Cancers.

Penile cancer (PeCa) is a rare urological malignancy characterized by significant geographical variations in both incidence and mortality rates. Due to its rarity and the consequent lack of randomized trials, current management is based on retrospective studies and small prospective trials. In addition, both the diagnostic pathways and treatment strategies exhibit substantial heterogeneity, differing significantly between less-developed and well-developed countries. The prognosis of PeCas is determined by the presence and extent of regional lymph node (LN) involvement. Therefore, the early detection and treatment of LN metastasis is paramount to ensure better outcomes. In recent decades, overall survival of PeCas has increased, mainly due to advancements in imaging techniques and risk stratification. We aim to provide an overview of the current role of PET CT imaging in the management of patients with PeCa.

Journal of clinical medicine. 2024 Aug 18*** epublish ***

Cristian Mirvald, Radion Garaz, Ioanel Sinescu, Adrian Preda, Apostolos Labanaris, Ofer Yossepowitch, Igor Tsaur, Cristian Surcel

Department of Urology, Fundeni Clinical Institute, 022328 Bucharest, Romania., Department of Urology, University Hospital Tübingen, 72076 Tübingen, Germany., Department of Urology, Interbalkan Medical Center, 57001 Thessaloniki, Greece., Department of Urology, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, Israel.