We compared the efficacy of Impaza (antibodies against endothelial NO-synthase in ultra-low doses) and Serenoa repens on the rat model of chronic aseptic prostatic inflammation.
Administration of Serenoa repens in a dose of 50 mg/kg for 1.5 months prevented the development of prostate sclerosis and increased luminal area, but did delay the development of atrophic processes. In animals treated with Impaza (3 ml/kg for 1.5 months), atrophic changes in the prostate gland were practically absent. These findings indicate that Impaza can be used in complex therapy of abacterial prostatitis.
Written by:
Borovskaya TG, Fomina TI, Pakhomova AV, Ermolaeva LA, Poluektova ME, Zhavbert ES, Dugina JL, Kheifets IA, Epstein OI. Are you the author?
Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia.
Reference: Bull Exp Biol Med. 2012 Dec;154(2):217-9.
PubMed Abstract
PMID: 23330129
