Prostate-specific membrane antigen (PSMA) is a cell surface glycoprotein, which is frequently overexpressed on prostate cancer cells. A Ga-PSMA PET/CT can be used for early detection of lymph node or bone metastases after radical prostatectomy when there is biochemical recurrence.
This report describes PSMA uptake in a healing fracture masquerading as metastatic bone disease in a patient with a history of prostate adenocarcinoma. Clinicians reporting Ga-PSMA PET/CT should be aware of this potential important pitfall.
Clinical nuclear medicine. 2016 Apr 06 [Epub ahead of print]
Pieterjan Gykiere, Lode Goethals, Hendrik Everaert
From the Departments of *Nuclear Medicine and †Radiology, University Hospital Brussel, Belgium.