To evaluate the accuracy of a new fluorine-18-2-fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) method when applying an increased upper limit of the image threshold (IULIT) to detect bladder cancer. All patients with an unknown history of bladder tumors were retrospectively included for analysis. Applying an IULIT in PET showed a hypermetabolic focus. 18F-FDG accumulation in the bladder that was higher or lower than the urinary level of 18F-FDG was considered an abnormal focus. In 12 of the 28,767 patients with bladder cancer, applying an IULIT in PET allowed the visualization of the contrast between lesion and urinary activity. The proposed method could increase the accuracy of detection of bladder cancer.
Written by:
Chen YK, Yeh CH, Su CT, Tsui CC, Cheng RH, Hung GU, Kao CH Are you the author?
Department of Nuclear Medicine and PET Center, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
Reference: Technol Cancer Res Treat. 2013 Nov 4. (Epub ahead of print)
doi: 10.7785/tcrt.2012.500383#sthash.klXuldY9.dpuf
PubMed Abstract
PMID: 24206206
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