Radical cystectomy and urinary diversion is regarded as the gold standard treatment for muscle-invasive bladder cancer without detectable hematogenous or lymphogenous metastases.
[1,2] This traumatic event is associated with significant changes in urinary and sexual function, interpersonal relationships, and psychosocial stress which ultimately impact patient's perceived quality of life.[3] In the past decade, there has been an increasing focus on quality of life outcomes in urological malignancies. This has been aided by the development of new health related quality of life (HRQOL) instruments for use specifically in urology. HRQOL is a patient centered outcome which can be defined as a patient's evaluation of the impact of a health condition and its treatment on relevant aspects of life. [4] There are quality of life differences between various diversions after radical cystectomy. However, few studies have documented superiority of orthotopic neobladder as compared to other forms of diversion but the current literature has many limitations and systemic reviews do not conclusively document the superiority of one form of diversion over the other in terms of quality of life (QoL).[3,5,6] In the present study, we tried to find out the perceived quality of life difference after radical cystectomy with ileal conduit versus orthotopic neobladder in a prospective longitudinal fashion.
Written by:
Singh V, Yadav R, Sinha RJ, Gupta DK. Are you the author?
Department of Urology, King George Medical University, Lucknow-226003, Uttar Pradesh, India.
Reference: BJU Int. 2013 Sep 5. Epub ahead of print.
doi: 10.1111/bju.12440
PubMed Abstract
PMID: 24053658
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