PURPOSE: To estimate the annual incidence of bladder cancer (BC) in Spain and to describe the clinical profile of BC patients enrolled in a population-based study.
MATERIALS AND METHODS: Using the structure of the Spanish National Health System as a basis, in 2011, the Spanish Association of Urology (AEU) conducted this study with a representative sample from 26 public hospitals and a reference population of 10,146,534 inhabitants, comprising 21.5% of the Spanish population.1
RESULTS: A total of 4,285 episodes of BC were diagnosed, 2,476 (57.8%) of which were new cases and 1,809 (42.2%) recurrences, representing an estimated 11,539 new diagnoses annually in Spain. The incidence of BC in Spain, age-adjusted to the standard European population, is 20.08 cases per 100,000 inhabitants (95% CI: 13.9; 26.3). Of patients diagnosed with first episode BC, 84.3% were male, generally aged over 59 (81.7%), with a mean age of 70.5 ± 11.4, and 87.5% presented some type of clinical symptom, with macroscopic hematuria (90.8%) being the most commonly detected. The majority of primary tumors were non-muscle-invasive (NMIBC) (76.7%), but included a high proportion of high-grade tumors (43.7%). According to the ISUP/WHO (2004) classification, 51.1% were papillary high-grade carcinoma. Carcinoma in situ (CIS) was found in 2.2% of primary and 5.8% of recurrent cases.
CONCLUSIONS: The incidence of BC in Spain, age-adjusted to the standard European population, confirms that Spain has one of the highest incidences in Europe. Most primary NMIBC correspond to high risk patients, but with a very low detected incidence of CIS.
Written by:
Miñana B, Cózar JM, Palou J, Unda Urzaiz M, Medina-Lopez RA, Subirá Ríos J, de la Rosa-Kehrmann F, Chantada-Abal V, Lozano F, Ribal MJ, Rodríguez Fernández E, Castiñeiras Fernández J, Concepción Masip T, Requena-Tapia MJ, Moreno-Sierra J, Hevia M, Gómez Rodríguez A, Martínez-Ballesteros C, Ramos M, Amón Sesmero JH, Pizá Reus P, Bohorquez Barrientos A, Rioja Sanz C, Gomez-Pascual JA, Hidalgo Zabala E, Parra Escobar JL, Serrano O. Are you the author?
Urology Department, Hospital Morales Meseguer, Chairman of Urology Department at Universidad Católica San Antonio, UCAM, Murcia, Spain.
Reference: J Urol. 2013 Aug 28. pii: S0022-5347(13)05276-2.
doi: 10.1016/j.juro.2013.08.049
PubMed Abstract
PMID: 23994371
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