Non-muscle-invasive bladder cancer is characterized by frequent recurrences requiring repeated transurethral resections and carries a risk of progression to muscle-invasive disease.
The routinely used, passive diffusion irrigation of the bladder with mitomycin C has achieved limited success in avoiding these events. We review two methods that may improve penetration of mitomycin C into the bladder wall, thus leading to better results in terms of recurrence rate and bladder preservation.
Written by:
Freifeld Y, Dekel Y, Stein A. Are you the author?
Department of Urology, Carmel Medical Centre, 7 Michal Street, Haifa, Israel.
Reference: Curr Urol Rep. 2013 Jan 19. Epub ahead of print.
doi: 10.1007/s11934-012-0302-9
PubMed Abstract
PMID: 23334670
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