Bacille Calmette-Guérin (BCG) immunotherapy is widely used for the treatment of superficial bladder cancer.
The authors believe that the present report is one of the first to document cerebral BCG tuberculoma in a 73-year-old immunocompetent man, three years after intra-vesical BCG immunotherapy. His workup revealed no identifiable extracranial source. He responded well to treatment with rifampin, ethambutol and moxifloxacin.Patients undergoing intravesical BCG therapy should be closely monitored for the development of this complication. Prolonged antitubercular therapy, possibly including moxifloxacin, appears to be beneficial in the treatment of central nervous system tuberculous infections.
Written by:
Golub V, Malhotra P, Patel S. Are you the author?
Sections of Infectious Diseases and Radiology, North Shore University Hospital, Manhasset, New York.
Reference: Can J Infect Dis Med Microbiol. 2011 Fall;22(3):104-6.
PubMed Abstract
PMID: 22942888
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