Functioning adrenocortical carcinomas are rare diseases with dismal prognosis.
A 41-year-old man presenting with gynecomastia had a giant feminizing adrenocortical carcinoma at stage IV. Although surgical resection was controversial, we removed the primary tumor to reduce the mass effects. He lived for 12 months with an acceptable quality of life. Gynecomastia may be the first sign of feminizing adrenal malignancies. Surgery may ameliorate the quality of life in selected patients with metastatic disease.
Written by:
Fancellu A, Pinna A, Porcu A. Are you the author?
Unit of General Surgery 2, Department of Clinical and Experimental Medicine, University of Sassari, Italy.
Reference: Clin Pract. 2014 Jul 9;4(2):651.
doi: 10.4081/cp.2014.651
PubMed Abstract
PMID: 25332762