Although myelolipomas of the adrenal glands are detected with increasing frequency with advances in imaging, the occurrence of myelolipoma with adrenal cortical carcinoma remains very rare.
We present a case of combined myelolipoma with adrenal cortical carcinoma in a 47-year-old man. In previously reported cases of adrenal cortical carcinoma and myelolipoma, the latter occurred as incidental foci within or peripheral to the carcinoma, perhaps representing "myelolipomatous metaplasia" rather than true neoplasia. We describe a new finding, in which the myelolipomatous component consisted of a large mass adjacent and dominant to the carcinoma. The presence of these 2 defined and apparently independent tumors suggests, in this case, the occurrence of collision or synchronous neoplastic events, rather than of metaplasia.
Written by:
Wang J, Fisher C, Thway K. Are you the author?
Royal Marsden Hospital, London, UK.
Reference: Int J Surg Pathol. 2014 Apr 29. Epub ahead of print.
doi: 10.1177/1066896914532538
PubMed Abstract
PMID: 24788531
UroToday.com Adrenal and Kidney Conditions Section
