We report the cases of 2 women who had urethral bulking injections with polydimethylsiloxane for stress urinary incontinence with intrinsic sphincter deficiency and reported initial improvement of symptoms followed by rapid return of stress urinary incontinence several weeks later associated with extrusion of the bulking material. We hypothesize this unique adverse outcome could represent immune rejection of this urethral bulking agent.
Female pelvic medicine & reconstructive surgery. 2016 Dec 01 [Epub ahead of print]
Alaina Town Bennett, Emily Spencer Lukacz
From the Department of Reproductive Medicine, University of California, San Diego, San Diego, CA.