Granulosa cell tumors (GCT) of the ovary are rare tumors that represent 2% of all ovarian tumors. However, cases involving the retroperitoneum are exceedingly rare.
We describe a case of primary retroperitoneal granulosa cell tumor, which, to our knowledge, has been previously reported in few cases.
A 64-year-old female presented with large intra-abdominal mass and vague abdominal pain. She had a history of hysterectomy and bilateral salpingo-oopherectomy 22 years ago for large uterine leiomyoma. She underwent exploratory laparotomy that revealed a retroperitoneal mass measuring 11 cm x 13 cm in size, with multiple cyst formation and areas of necrosis and hemorrhage. The gross, histologic, and inhibin-positive immunostaining findings of the retroperitoneal mass were characteristic of adult-type GCT. Excluding any previous history of primary ovarian GCT with this patient, a de-novo retroperitoneal diagnosis was carried out.
KEYWORDS: Granulosa cell tumors, retroperitoneum, inhibin
CORRESPONDENCE: Yousef Al-Shraideh, MD, King Fahad Medical City, Riyadh, Riyadh, Saudi Arabia
CITATION: UroToday Int J. 2012 December;5(6):art 61.
DOI: http://dx.doi.org/10.3834/uij.1944-5784.2012.12.11
