The objective of this study was to investigate the relationship between situational cues (running water, stress, cold, etc.) and overactive bladder (OAB) symptoms.
Women scheduled for urodynamic studies for clinical indications completed surveys to characterize OAB (ICIQ-OAB and OAB-V3) and responses to situational cues (validated long-form cues survey and a novel short-form cues survey). Participants were divided into two groups (Low-Bother urgency vs. High-Bother urgency), and OAB and cue survey responses were compared.
A total of 47 participants were enrolled in the study with 36 meeting inclusion criteria (15 Low-Bother and 21 High-Bother) with an overall mean age of 60.0 ± 10.0 years. The High-Bother urgency group scored significantly higher on multiple cue items in the long-form (P<0.05) and only "running water" in the short-form cues survey (P<0.05). In addition, "running water" was the only cue that was scored higher in both surveys (P<0.05).
This study showed that patients with High-Bother urgency may have increased symptom responses to environmental, mood, and cognitive cues. These findings suggest increased sensitivity to cues, especially "running water" in participants with bothersome OAB and the potential presence of a cue-specific OAB phenotype.
American journal of clinical and experimental urology. 2024 Aug 25*** epublish ***
Sarah T Kodama, Ria Khandpur, Jared Dunlap, Julia Smolen, Chris Keshishian, Kathleen A O'Connell, Linda S Burkett, Lauren N Siff, John E Speich, Adam P Klausner
Department of Surgery/Division of Urology, Virginia Commonwealth University School of Medicine Richmond, VA, USA., Department of Health and Behavior Studies, Columbia University New York, NY, USA., Department of Obstetrics and Gynecology, Virginia Commonwealth University Richmond, VA, USA., Department of Mechanical and Nuclear Engineering of Engineering, College of Engineering, Virginia Commonwealth University Richmond, VA, USA.