AIMS: To explore the risk factors of nocturia in Chinese inhabitants aged ≥40 years.
METHODS: A randomized, community-based, cross-sectional study was performed on 10,160 inhabitants ≥40 years old in mainland China, via a stratified sampling approach. A questionnaire, including socio-demographics, lifestyle factors and medical history, was completed. Nocturia was defined as a threshold of two or more voids per night. Differences in prevalence between age and gender groups were ascertained by the chi-squared test. Gender-related factors were evaluated by multivariate logistic regression analysis. P < 0.05 was considered to be statistically significant.
RESULTS: Data on 9,637 (94.9%) people aged 59.6 ± 9.7 years qualified for final statistical analysis. The overall prevalence of nocturia was 31.7% (3,053/9,637), and this increased with age (P < 0.001). Nocturia was significantly associated with cardiovascular disease and overactive bladder symptom score (OABSS) (P < 0.05), while sporting activities were protective (P < 0.001). Diabetes mellitus (DM) was significantly correlated with nocturia in men (P < 0.05), whereas hypertension was correlated with nocturia in women (P < 0.05). No correlation was found between nocturia and education level, occupation, civil status, tea consumption, body mass index (BMI), female birth history, and International Prostate Symptom Score.
CONCLUSIONS: In Chinese people aged ≥40 years, nocturia is associated with aging, OABSS, cardiovascular disease, hypertension, and DM. Sporting activities are negatively associated with nocturia.
Written by:
Wen L, Wen YB, Wang ZM, Wen JG, Li ZZ, Shang XP, Liu ZS, Jia LH, Qin GJ, Heesakkers J, Corcos J, Djurhuus JC. Are you the author?
Urodynamics Centre, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Department of Nephrology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Institute of Clinical Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Reference: Neurourol Urodyn. 2014 Apr 30. Epub ahead of print.
doi: 10.1002/nau.22623
PubMed Abstract
PMID: 24788681