PURPOSE: The objective of this study was to investigate the long-term prognosis of a cohort of children with nocturnal enuresis (NE) and to identify prevalence of nocturia and persistent comorbid symptoms.
MATERIAL & METHODS: A questionnaire was sent to 1265 patients treated during childhood for NE at the Ghent University Hospital, Belgium. To evaluate presence of current urological symptoms validated questionnaires were used, the International Consultation on Incontinence modular Questionnaire on overactive bladder (ICIQ-OAB) and urinary incontinence (ICIQ-UI). Participants were also asked about the treatment they received for NE and their medical files were analyzed.
RESULTS: Five-hundred-and-sixteen patients (41%) returned the questionnaire. Mean age is 17 years, 64% are male patients. Current urgency, daytime frequency and UI are reported by 17%, 8% and 25%, respectively. During the period of NE, up to 60% has concomitant daytime symptoms. Nocturia is reported by 182 participants (35%), 101 (56%) are male versus 230 of 334 (69%) in those without nocturia. Prevalence of current daytime symptoms and incontinence is higher in patients with nocturia (p<0.001). Those who develop nocturia were older at age of cure of NE (p<0.001) and suffered more NMNE (p<0.014).
CONCLUSIONS: About 1/3 develops nocturia, 1/4 still reports some kind of UI, 1/5 regular urgency and 1/10 daytime frequency. It seems that cure of NE does not necessarily means cure of the underlying pathology and some of the nocturia patients, who continue to suffer bothersome symptoms, might benefit from continuous treatment for the underlying condition.
Written by:
Goessaert AS1, Schoenaers B2, Opdenakker O3, Hoebeke P4, Everaert K4, Walle JV5 Are you the author?
1Urology Department, Ghent University Hospital, Belgium. Electronic address: . 2Ghent University, Belgium. 3Department of Anesthesia, Ghent University Hospital, Belgium. 4Urology Department, Ghent University Hospital, Belgium. 5Pediatric Nephrology Department, Ghent University Hospital, Belgium.
Reference: J Urol. 2014 Jan 11. pii: S0022-5347(14)00008-1 (Epub ahead of print)
doi: 10.1016/j.juro.2013.12.051
PubMed Abstract
PMID: 24423434
