To assess the impact of nocturnal continuous positive airway pressure (CPAP) treatment of obstructive sleep apnea (OSA) on lower urinary tract (LUTS) symptoms.
A prospective, monocentric study was conducted between June 2018 and August 2019. Patients with moderate to severe OSA with an indication for treatment with nocturnal CPAP in combination with SBAU were included. SBAUs and their impact were evaluated by completing two self-administered questionnaires (Urinary Symptom Profile (USP) and International Prostate Score Symptom (IPSS)) filled out during the night-time ventilatory polygraph or diagnostic polysomnography for OSA and after 4 months of CPAP treatment.
In 79 patients, after four months of CPAP treatment, USP scores for stress urinary incontinence and overactive bladder were significantly improved, respectively 0.65±1.38 vs 1.13±2.10 ; p<0.0001 and 3.24±2.58 vs 5.43±3.66 ; p<0.0001, IPSS and IPSS-Qdv were significantly improved, respectively 5.20±3.78 vs. 7.44±5.05 ; p<0.0001 and 1.93±1.26 vs. 2.27±1.56 ; p=0.002 as well as IPSS score items on pollakiuria, urgency and nocturia.
Treatment with CPAP significantly improved SBAU in four months. Testing urology patients for symptoms of OSA in urology patients seeking SBAU would allow referral of patients suspected of OSA to a specialist for diagnosis and management if necessary.
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie. 2021 Jun 19 [Epub ahead of print]
R Seret, C Launois, C Barbe, S Larre, P Léon
Service d'urologie, centre hospitalier universitaire Reims, rue du Général-Koenig, 51100 Reims, France. Electronic address: ., Service des maladies respiratoires, unité de sommeil et ventilation, centre hospitalier universitaire Reims, 51100 Reims, France., Service de santé publique et d'aide méthologique, centre hospitalier universitaire Reims, 51100 Reims, France., Service d'urologie, centre hospitalier universitaire Reims, rue du Général-Koenig, 51100 Reims, France., Service d'urologie, clinique Pasteur, 17200 Royan, France.