The following is a report on the proceedings of the 2019 International Consultation on Incontinence-Research Society nocturia think tank (NTT).
The objectives of the 2019 NTT were as follows: (a) to evaluate the role of urothelium in the pathophysiology of nocturia; (b) to determine whether nocturia is a circadian disorder; (c) to discuss the role of melatonin in nocturia; (d) to consider ambulatory urodynamic monitoring in evaluating patients with nocturia; (e) to explore studies of water handling in human compartments utilizing heavy water; and (f) to explore whether basic science is the key to understanding the treatment options for diminished bladder capacity in patients with nocturia.
A compendium of discussions of the role of experimental science in understanding the pathophysiology of nocturia is described herein.
Translational science will play an increasing role in understanding the pathophysiology of nocturia, which may result in improved treatment strategies.
Neurourology and urodynamics. 2020 Jan 10 [Epub ahead of print]
Bahareh Vahabi, Rita Jabr, Chris Fry, Karen McCloskey, Karel Everaert, Christina W Agudelo, Thomas F Monaghan, Mohammad S Rahnama'i, Jalesh N Panicker, Jeffrey P Weiss
Department of Applied Sciences, School of Physiology, Pharmacology, and Neuroscience, University of Bristol, Bristol, UK., Department of Cardiac Electrophysiology, University of Surrey, Guildford, Surrey, UK., School of Medicine, Dentistry and Biomedical Sciences, Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, Northern Ireland, UK., Department of Urology, Ghent University Hospital, Ghent, Belgium., Department of Urology, SUNY Downstate Health Sciences University, Brooklyn, New York., Department of Urology, Maastricht University Medical Centre, Maastricht, The Netherlands., Department of Neurology, National Hospital for Neurology and Neurosurgery, London, UK.