Subfertility is defined as the condition of being less than normally fertile though still capable of effecting fertilization. When these subfertile couples seek assistance for conception, a thorough evaluation of male endocrine function is often overlooked. Spermatogenesis is a complex process where even subtle alterations in this process can lead to subfertility or infertility. Male endocrine abnormalities may suggest a specific diagnosis contributing to subfertility; however, in many patients, the underlying etiology is still unknown. Optimizing underlying endocrine abnormalities may improve spermatogenesis and fertility. This manuscript reviews reproductive endocrine abnormalities and hormone-based treatments.
Current urology reports. 2016 Aug [Epub]
Darshan P Patel, Jason C Chandrapal, James M Hotaling
Division of Urology, Department of Surgery, University of Utah Health Care, 30 N 1900 E, Rm 3B420, Salt Lake City, UT, 84132, USA., Division of Urology, Department of Surgery, University of Utah Health Care, 30 N 1900 E, Rm 3B420, Salt Lake City, UT, 84132, USA. ., Division of Urology, Department of Surgery, University of Utah Health Care, 30 N 1900 E, Rm 3B420, Salt Lake City, UT, 84132, USA.