BACKGROUND: The assisted reproductive techniques aimed to assist infertile couples have their own offspring carry significant risks of passing on molecular defects to next generations.
RESULTS: Novel breakthroughs in gene and protein interactions have been achieved in the field of male infertility using genome-wide proteomics and transcriptomics technologies.
CONCLUSION: Male Infertility is a complex and multifactorial disorder.
SIGNIFICANCE: This review provides a comprehensive, up-to-date evaluation of the multifactorial factors involved in male infertility. These factors need to be first assessed and understood before we can successfully treat male infertility.
Written by:
Tahmasbpour E, Balasubramanian D, Agarwal A. Are you the author?
Department of Biology, Islamic Azad University, Sari, Iran.
Reference: J Assist Reprod Genet. 2014 Aug 13. Epub ahead of print.
doi: 10.1007/s10815-014-0280-6
PubMed Abstract
PMID: 25117645
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