Clomiphene citrate, a selective estrogen receptor modulator, has been used to treat infertility in women and men for 50 years.
In men, clomiphene citrate has been employed in the management of unexplained infertility, oligo and asthenospermia, hypogonadism, and nonobstructive azoospermia. The available evidence reveals mixed results and suggests that clomiphene citrate may be appropriate for the management of male infertility in specific clinical scenarios. Further research is needed to clarify when clomiphene citrate is indicated in the treatment of male infertility.
Written by:
Roth LW, Ryan AR, Meacham RB. Are you the author?
Department of Obstetrics and Gynecology, University of Colorado, Denver, Colorado.
Reference: Semin Reprod Med. 2013 Jul;31(4):245-50.
doi: 10.1055/s-0033-1345271
PubMed Abstract
PMID: 23775379
UroToday.com Male Infertility & Reproduction Section
