To compare the prevalence of chronic periodontitis between men who had semen abnormalities and those who had normozoospermia through a case-control study.
Male patients who visited the assisted reproduction clinic of a large general hospital and were diagnosed with semen abnormalities were included in the case group. The control group was composed of patients of the same clinic with normozoospermia. The semen analysis included sperm concentration, count and progressive and total motility, which were measured in the laboratory. A questionnaire and clinical periodontal examination were conducted for all participants. Logistic regression was performed to explore the relationship between chronic periodontitis and male infertility.
A total of 192 participants were included: 63 participants (32.8%) had some type of semen abnormality (case group), while 129 participants (67.2%) had normozoospermia (control group). The case group had a significantly higher prevalence of moderate/severe periodontitis than the control group (33.3% vs. 17.8%, P=0.012). The logistic regression showed that participants who had moderate/severe periodontitis had a greater chance of having semen abnormalities after adjusting for other confounding factors (OR=3.377, P=0.005).
Periodontitis is associated with semen abnormalities and sperm motility in men.
Oral diseases. 2020 Jul 23 [Epub ahead of print]
Dan-Ying Tao, Jia-Lin Zhu, Chun-Yu Xie, Yan-Ping Kuang, Wei-Ran Chai, Edward Chin Man Lo, Wei Ye, Fei Li, Xi-Ping Feng, Hai-Xia Lu
Department of Preventive Dentistry, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University, School of Medicine, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, 639 Zhizaoju Road, Shanghai, China., Department of Assisted Reproduction, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, China., Dental Public Health, Faculty of Dentistry, University of Hong Kong, 34 Hospital Road, Hong Kong, China.