To determine the sperm retrieval rates(SRRs) and predictive factors of patients with a history of undescended testis after testicular sperm extraction (TESE).
A total of 311 patients were diagnosed with non-obstructive azoospermia (NOA) and underwent TESE were included in this study. These patients were divided into two groups: an undescended group consisting of 62 patients who had a history of undescended testes and an idiopathic group consisting of 249 patients. Of the 62 patients with a history of undescended testes, 26 had a history of bilateral orchidopexy, 15 had a history of unilateral orchidopexy, and 21 had no history of surgery.
The testicular spermatozoa were found in 134 (53.8%) and 31 (50%) patients in the idiopathic NOA and undescended testes groups, respectively. Similar to patients with idiopathic NOA, the overall SRRs were strongly associated with histopathology for patients with a history of undescended testes. These SRRs were 34.2%, 33.3%, 71.4%, 100%, and 100% for Sertoli Cell Only, late maturation arrest, early maturation arrest, hypospermatogenesis, and normal spermatogenesis, respectively(p<0.001). In the undescended group, the SRRs of patients who underwent orchidopexy were not different than patients without a history of orchidopexy. However, patients who underwent unilateral orchidopexy had a higher SRR than those who underwent bilateral orchidopexy(p=0.031).
TESE is a successful treatment modality for men with NOA associated with or without a history of undescended testis. The testicular histopathology and unilateral undescended testis were identified as independent predictors of SRRs for men with a history of undescended testis.
Urology. 2020 Apr 14 [Epub ahead of print]
Mazhar Ortac, Nusret Can Cilesiz, Erhan Demirelli, Reşat Aydın, Metin Savun, Bahadır Ermeç, Ateş Kadıoğlu
Urology Department, Faculty of Medicine, Istanbul University, Istanbul, Turkey. Electronic address: ., Urology Department, Faculty of Medicine, Istanbul University, Istanbul, Turkey. Electronic address: ., Urology Department, Faculty of Medicine, Istanbul University, Istanbul, Turkey. Electronic address: ., Urology Department, Faculty of Medicine, Istanbul University, Istanbul, Turkey; Urology Deparment, Siverek State Hospital, Şanlıurfa, Turkey. Electronic address: ., Urology Deparment, Siverek State Hospital, Şanlıurfa, Turkey. Electronic address: ., Urology Department, Faculty of Medicine, Istanbul University, Istanbul, Turkey. Electronic address: ., Urology Department, Faculty of Medicine, Istanbul University, Istanbul, Turkey. Electronic address: .