With the increasing trend ofpopulation aging, erectile dysfunction (ED) among elderly men has emerged as apressing health concern. Despite extensive research on the relationship betweenED and aging, ongoing discoveries and evidence continue to arise.
Through this comprehensiveanalysis, we aim to provide a more nuanced theoretical framework for thedevelopment of preventive and therapeutic strategies for senile ED, ultimatelyenhancing the quality of life for elderly men.
This review delves deeper into thecore mechanisms underlying ED in the context of aging and offers acomprehensive overview of published meta-analyses and systematic reviewspertinent to these conditions.
Our findings revealthat local structural damage to the penis, vascular dysfunction, neuronalinjury, hormonal alterations, other physiological changes, and psychologicalbarriers all play pivotal roles in the pathogenesis of aging-related ED.Furthermore, more than 20 diseases closely associated with aging have beenimplicated in the occurrence of ED, further compounding the complexity of thisissue.
Andrology. 2024 Oct 09 [Epub ahead of print]
Baojun Zhuang, Chenglin Zhuang, Yongze Jiang, Jingyi Zhang, Yandong Zhang, Peihai Zhang, Xujun Yu, Suyun Xu
Yunnan University of Chinese Medicine, Kunming, P. R. China., Department of Urology at the Second Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine, Xianyang, P. R. China., TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, P. R. China., Luohe Medical College, Luohe, P. R. China., The First People's Hospital of Yunnan Province/The Affiliated Hospital of Kunming University of Science and Technology, Kunming, P. R. China.