To evaluate the long-term outcomes and safety photoselective vaporization of the prostate (PVP).
From April 2005 to December 2015, a total of 1154 patients with benign prostatic hyperplasia (BPH) underwent PVP. The type of Green Light laser was an 80W potassium-titanyl-phosphate (KTP) laser and later a 120W lithium triborate (LBO) laser. Before and after surgery, the International Prostate Symptom Score (IPSS), maximum urinary flow rate (Qmax), post-void residual volume (PVR), prostate-specific antigen (PSA) level and prostate volume were assessed regularly. After surgery, events such as second PVP, transurethral incision, and permanent urethral catheterization were defined as re-treatment.
The mean and median periods of follow-up after PVP were 35.4 and 24.0 months, respectively. The maximum duration of follow-up was 125 months. Compared with before surgery, the IPSS, QOL score and PSA concentration improved significantly, even at 10 years after PVP; however, Qmax and PVR were not improved at 10 years. The re-treatment-free survival rate was 93.9% at 5 years and 79.0% at 10 years. Prostate cancer was found in 27 cases after PVP, and all patients who were diagnosed with prostate cancer remained alive. Prostate cancer-free survival after PVP was 96.7% at 5 years, and 89.4% at 10 years.
Our data suggest that the efficacy of PVP was maintained for 10 years; however, it may decrease after more than 10 years. PVP also did not promote the progression of or worsen the prognosis of prostate cancer.
Journal of endourology. 2016 Oct 12 [Epub ahead of print]
Yasushi Yamada, Jun Furusawa, Yoshiki Sugimura, Isao Kuromastu
Nagoya Central Byoin, 73715 , 3-7-7 Taiko , Nakamura-ku , Nagoya , Nagoya, Japan , 453-0801 ; ., Nagoya Central Byoin, 73715, Nagoya , 3-7-7 Taiko , Nakamura-Ku , Nagoya , Nagoya, Japan , 453-0801 ; ., Mie Daigaku, 12946, Urology , Edobashi 2-174 , Tsu, Japan , 514-8507 ; ., Nagoya Central Byoin, 73715, Urology , Taiko 3-7-7 , Nakamura-Ku , Nagoya , Nagoya, Japan , 453-0801 ; .