The medicoeconomic issues of drug management of benign prostatic hyperplasia (BPH) are essential due to the aging population and the increasing number of therapeutic options. It is thus essential to assess the cost-effectiveness in order to define the most appropriate therapeutic strategies economically.
The objective of this work was to conduct a literature review on the medicoeconomic studies on the drug therapy of BPH.
After analyzing the literature, 43 articles were found and 9 were selected for their relevance.
Based on Markov models, we observed that: combination therapy and combined treatments (alphablockers and inhibitors of 5-alpha reductase [5ARI]) seemed to have the best cost-effectiveness. Then came the alphablockers, less expensive but exposing to a greater risk of progression and to the necessity of surgical treatments. Then came the 5ARI monotherapy and finally simple monitoring.
The Markov models are imperfect tools, and resources invested in care depend on both the economic model and the value that individuals and society give to efficiency and cost.
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie. 2015 Nov 28 [Epub ahead of print]
S Lebdai, A R Azzouzi, N-B Delongchamps, A Benchikh, A Campeggi, J-N Cornu, O Dumonceau, A Faix, M Fourmarier, O Haillot, B Lukacs, R Mathieu, V Misrai, G Robert, A de La Taille, A Descazeaud
Service d'urologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9, France. Service d'urologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9, France. , Service d'urologie, CHU Cochin, 75014 Paris, France. , Service d'urologie, hôpital Bichat - Claude-Bernard, groupe des hôpitaux universitaires Paris-Nord-Val-de-Seine, université Denis-Diderot Paris-VII, 75018 Paris, France. , Service d'urologie, CHU Mondor, 75000 Paris, France. , Service d'urologie, CHU de Rouen, 1, rue de Germont, 76031 Rouen cedex, France. , Service d'urologie, clinique Turin, 75008 Paris, France. , Clinique mutualiste Beausoleil, 34070 Montpellier, France. , Service d'urologie, centre hospitalier Aix-en-Provence, 13616 Aix-en-Provence, France. , Service d'urologie, CHU de Tours, 37044 Tours, France. , Service d'urologie, clinique Turin, 75008 Paris, France. , Service d'urologie, hôpital Pontchaillou, CHU de Rennes, 35000 Rennes, France. , Service d'urologie, clinique Pasteur, 31300 Toulouse, France. , Service d'urologie, université Bordeaux-Segalen, CHU de Bordeaux, 33076 Bordeaux, France. , Service d'urologie, CHU Mondor, 75000 Paris, France. , Service de chirurgie urologique, CHU de Limoges, 87042 Limoges, France.