To compare the prevalence of (1) the metabolic syndrome and (2) the components of the metabolic syndrome in men aged 50 years and older with and without clinical benign prostate hyperplasia (BPH).
This was a cross-sectional study using the UK Clinical Practice Research Database (CPRD).
Men were selected from the UK CPRD that were ≥50 years of age and still registered as of 31st December 2011. Cohort 1 included men with clinical BPH, and cohort 2 men without clinical BPH that were matched 1:1 to those in cohort 1 by general practice, year of birth and prior years of available history (1 to
A total of 26. 5% of men with clinical BPH had the metabolic syndrome compared with 20. 9% of matched controls without clinical BPH (absolute difference 5. 6%; p
There is a significant cross-sectional association between clinical BPH and the metabolic syndrome in the UK primary care population. This article is protected by copyright. All rights reserved.
BJU international. 2015 Sep 22 [Epub ahead of print]
Julia R DiBello, Chris Ioannou, Jonathan Rees, Ben Challacombe, Joe Maskell, Nurul Choudhury, Christof Kastner, Mike Kirby
GSK, Collegeville, Pennsylvania, United States. , GSK, Uxbridge, Middlesex, UK. , Backwell and Nailsea Medical Group, North Somerset, UK. , Department of Urology, Guy's and St Thomas' Hospital, London, UK. , GSK, Uxbridge, Middlesex, UK. , West Middlesex University Hospital NHS Trust, Isleworth, UK. , Cambridge University Hospitals, Cambridge, UK. , Faculty of Health and Human Sciences, University of Hertfordshire, Hatfield, UK.