The Co-occurring Syndrome-Coexisting Erectile Dysfunction and Benign Prostatic Hyperplasia and Their Clinical Correlates in Aging Men: Results From the National Health and Nutrition Examination Survey

To establish a descriptive profile of men with coexistent erectile dysfunction (ED) and/or benign prostatic hyperplasia (BPH), ED only or BPH only compared to those with neither condition and to identify the determinants of coexisting disease.

Self-report and/or medication use measures defining ED and BPH were assessed in men aged ≥40 years (N = 2142) between 2001 and 2004 using the National Health and Nutrition Examination Surveys. Descriptive analyses examined the ED and/or BPH covariate distribution. Logistic regressions calculated odds ratios (ORs, 95% confidence interval) comparing men with ED and/or BPH, BPH only, or ED only to men with neither condition.

Of 393 men with BPH, 57. 8% had coexistent ED, confirming the moderately strong co-occurrence of the conditions (P 

Co-occurring ED and/or BPH is evident in ∼10% of men ≥40 years old and is associated with significant clinical correlates. Clinicians need to pay greater attention to this clinically important syndrome in aging men.

Urology. 2015 Jun 17 [Epub ahead of print]

Kathryn B Egan, Arthur L Burnett, Kevin T McVary, Xiao Ni, Minhyung Suh, David G Wong, Raymond C Rosen

New England Research Institutes, Inc. , Watertown, MA. Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD. , Division of Urology, Southern Illinois University School of Medicine, Springfield, IL. , Global Statistical Sciences and Advanced Analytics, Eli Lilly and Company, Indianapolis, IN. , New England Research Institutes, Inc. , Watertown, MA. , Eli Lilly and Company USA, Indianapolis, IN. , New England Research Institutes, Inc. , Watertown, MA.

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