The decline in testosterone with age has been associated with specific physical changes that affect quality of life and life expectancy, although a cause-and-effect relationship is yet to be established.
While female menopause is rapid and well described, "male menopause" or androgen decline in older men is gradual and marked by nonspecific symptoms. This makes diagnosis of true testosterone deficiency and prediction of response to testosterone replacement therapy (TRT) challenging.
Written by:
McGill JJ, Shoskes DA, Sabanegh ES. Are you the author?
Urology Institute, University Hospitals Case Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106.
Reference: Cleve Clin J Med. 2012 Nov;79(11):797-806.
doi: 10.3949/ccjm.79a.12010
PubMed Abstract
PMID: 23125330
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