High dose of vitamin C intake could increase urine oxalate excretion and hence the risk of calcium stone formation.
We report a case of left ureteral stone in a 9-year-old boy with an extremely high urine oxalate excretion. Besides, he had a habit of taking high-dose supplementation of vitamin C since the age of 3 years. After vitamin C intake prohibited without other therapy and change of dietary intake, the urine oxalate excretion was decreased to normal level and no recurrence of urolithiasis was present during the 3-year follow-up. Thus, high-dose supplementation with vitamin C for years in a child could induce the urinary stones.
Written by:
Chen X, Shen L, Gu X, Dai X, Zhang L, Xu Y, Zhou P. Are you the author?
Department of Urology, Jiangsu Province Hospital of Traditional Chinese Medicine, Nanjing, P.R. China.
Reference: Urology. 2014 Oct;84(4):922-4.
doi: 10.1016/j.urology.2014.07.021
PubMed Abstract
PMID: 25260453