Introduction: The incidence of nephrolithiasis has consistently been increasing over recent decades.
This has been attributed to diet, obesity, environmental temperature changes, and co-morbid diseases such as diabetes. Incidence change has not been studied in the pregnant population. Herein, we report our experience with stone diagnosis in this unique patient population over the past 2 decades.
Methods: Hospital data from a tertiary women's hospital was examined for ICD-9 codes for pregnancy (640-648, V22.0, V22.1, V22.2) and urolithiasis (592.0, 592.1, 592.9) between 1991 and 2011. The change in incidence in nephrolithiasis, pregnancy and the combination of both was examined.
Results: In the 21 year period studied, 876 pregnant patients were given a diagnosis of nephrolithiasis at our hospital. Over the same time, 204,034 pregnant patients and 3,262 stone patients were treated. Comparing patients seen from 1991-2000 to those seen from 2001-2011 revealed a significant increase in stone patients (78 vs. 226/year, p=0.004) but no change in pregnant patients (9467 vs. 9942/year, p=0.3) or pregnant patients with stones (36 vs. 47, p=0.1). Evaluating patients at 5-year intervals confirmed the expected increase in stone patients but no change in incidence of nephrolithiasis in pregnant patients was noted.
Conclusion: There was no change in incidence of nephrolithiasis in pregnant patients over a 2-decade period. Further research is warranted to determine why the pregnant population does not have the expected increase in nephrolithiasis. Larger, multi-institutional studies are needed to validate our results.
Written by:
Riley JM, Dudley AG, Semins MJ. Are you the author?
University of New Mexico, Surgery, MSC10 5610, 1 University of New Mexico, Albuquerque, New Mexico, United States, 87131, 5052725505.
Reference: J Endourol. 2013 Oct 22. Epub ahead of print.
doi: 10.1089/end.2013.0570
PubMed Abstract
PMID: 24147956
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