Focused ultrasonic propulsion of kidney stones: Review and update of preclinical technology - Abstract

Introduction: A noninvasive tool to reposition kidney stones could have significant impact in the management of stone disease. Our research group has developed a noninvasive transcutaneous ultrasound device. A review and update of the current status of this technology is provided.

Discussion of Technology: Stone propulsion is achieved through short bursts of focused, ultrasonic pulses. The initial system consisted of an 8-element annular array transducer, computer, and separate ultrasound imager. In the current generation, imaging and therapy are completed with one ultrasound system and a commercial probe. This generation allows real-time ultrasound imaging, targeting, and propulsion. Safety and effectiveness for the relocation of calyceal stones has been demonstrated in the porcine model.

Role in Endourology: This technology may have applications in repositioning stones as an adjunct to lithotripsy, facilitating clearance of residual fragments after lithotripsy, expelling de novo stones, and potentially repositioning obstructing stones. Human trials are in preparation.

Written by:
Sorensen MD, Bailey MR, Hsi RS, Cunitz BW, Simon J, Wang YN, Dunmire BL, Paun M, Starr F, Lu W, Evan AP, Harper JD.   Are you the author?
Department of Veteran Affairs Medical Center, Division of Urology, Seattle, Washington, United States; University of Washington, Department of Urology, 1959 NE Pacific Street, Box 356510, Seattle, Washington, United States, 98195.

Reference: J Endourol. 2013 Jul 24. Epub ahead of print.
doi: 10.1089/end.2013.0315


PubMed Abstract
PMID: 23883117

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