The qualitative and quantitative analyses of crystalluria have clinical significance in the diagnosis and prognosis of urolithiasis.
The aim of this paper is to provide a new accurate methodology to get qualitative and quantitative data on urine particulate in patients with renal stone disease.The procedure involves a urine collection, the separation of the solid residual by centrifugation, and its analysis by X-ray diffraction, utilizing a micro-diffractometer in order to analyze very low amounts of residual. The spectrum obtained was converted into 2 θ -I profiles and quantitatively refined by Rietveld method. The proposed methodology has the advantage to accurately quantify all crystalline phases and the amorphous component of the urine; anyway urine samples have to be centrifuged and analysed as soon as possible, because the quantitative results obtained by the X-ray microdiffraction showed that after some days and at room temperature urine increased significantly both amorphous and crystalline phases.
Written by:
Baggio B, Giannossi ML, Medici L, Summa V, Tateo F. Are you the author?
Dip. Scienze Mediche e Chirurgiche, UniversitĂ degli Studi di Padova, Padova, Italy.
Reference: J Xray Sci Technol. 2012 Jan 1;20(4):489-98.
doi: 10.3233/XST-2012-00355
PubMed Abstract
PMID: 23324789
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