Their objective was to examine the dietary factors implicated in risk for stones, specifically within the overweight population. Validated dietary questionnaires measured daily caloric and diet intake. Out of 78,551 participants in the study, 1,960 women developed at least one stone episode. BMI was found to be the strongest associated risk factor. Patients with BMI >40 had an unadjusted odds ratio of 2.4 for an episode of nephrolithiasis when compared with normal individuals. A diet of >2500 kcal/day was found to have a 1.5 odds ratio compared to a diet <1500 kcal/day, even after adjusting for BMI.
In summary, although obesity is the strongest risk factor for stone disease in this study, total caloric intake represented an independent risk factor for nephrolithiasis.
Presented by Thomas Chi, MD, et al. at the American Urological Association (AUA) Annual Meeting - May 14 - 19, 2011 - Walter E. Washington Convention Center, Washington, DC USA
Reported for UroToday by Phillip Mucksavage, MD, Department of Urology, University of California, Irvine.
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