The stricture-formation rate following ureteroscopy ranges from 0.5 to 5% and might amount to 24% in patients with impacted ureteral stones. The pathogenesis of ureteral stricture formation is not yet fully understood. It is likely that the patient and stone characteristics, as well as intervention factors, play a role in this process. In this systematic review, we aimed to determine the potential factors responsible for ureteral stricture formation in patients having impacted ureteral stones.
Following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) criteria, we conducted systematic online research through PubMed and Web of Science without a time restriction, applying the keywords "ureteral stone", "ureteral calculus", "impacted stone", "ureteral stenosis", "ureteroscopic lithotripsy", "impacted calculus", and "ureteral strictures" singly or in combination.
After eliminating non-eligible studies, we identified five articles on ureteral stricture formation following treatment of impacted ureteral stones. Ureteral perforation and/or mucosal damage appeared as key predictors of ureteral stricture following retrograde ureteroscopy (URS) for impacted ureteral stones. Besides ureteral perforation stone size, embedded stone fragments into the ureter during lithotripsy, failed URS, degree of hydronephrosis, nephrostomy tube or double-J stent (DJS)/ureter catheter insertion were also suggested factors leading to ureteral strictures.
Ureteral perforation during surgery might be considered the main risk factor for ureteral stricture formation following retrograde ureteroscopic stone removal for impacted ureteral stones.
Journal of clinical medicine. 2023 May 22*** epublish ***
Senol Tonyali, Mehmet Yilmaz, Lazaros Tzelves, Esteban Emiliani, Vincent De Coninck, Etienne Xavier Keller, Arkadiusz Miernik
Department of Urology, Istanbul Faculty of Medicine, Istanbul University, 34452 Istanbul, Turkey., Department of Urology, Faculty of Medicine, Medical Center, University of Freiburg, 79106 Freiburg, Germany., European Association of Urology, Young Academic Urologist Endourology and Urolithiasis Working Party, NL-6803 Arnhem, The Netherlands.