We aimed to evaluate the relationship between the proportion of Android to Gynoid ratio and the incidence of kidney stones among US adults.
Participants aged 20-59 years from the 2011-2018 National Health and Nutrition Examination Survey (NHANES) database were selected to assess the association between Android to Gynoid ratio and kidney stone prevalence using logistic regression analysis, subgroup analysis and calculation of dose-response curves.
This study ultimately included 10858 participants, of whom 859 self-reported a history of kidney stones. And after adjusting for all confounders, an increased Android to Gynoid ratio was associated with an increased prevalence of kidney stones (OR=2.75, 95% CI:1.62-4.88). And subgroup analysis showed an increased prevalence of kidney stones in women (OR=3.55, 95% CI: 1.54-8.22), non-diabetic (OR=2.59, 95% CI: 1.45-4.60), 60 > age ≥ 40 years (OR=3.51, 95% CI: 1.83-6.71), Mexican-American (OR=4.35, 95% CI: 1.40- 13.53) and white (OR=3.86, 95% CI: 1.82-8.18) groups, there was a significant positive association between A/G ratio and kidney stones. In contrast, in the hypertensive subgroup, the A/G ratio was associated with kidney stones in all groups.
Higher Android to Gynoid ratio is associated with a high prevalence of kidney stone disease.
Frontiers in endocrinology. 2022 Oct 07*** epublish ***
Guoxiang Li, Hu Liang, Yunwu Hao, Qingfeng Huang, Xudong Shen, Yang Chen, Mingwei Chen, Junhua Xi, Zongyao Hao
Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China., Department of Endocrinology, The First Affiliated Hospital of Anhui Medical University, Hefei, China., Department of Urology, The Second people's Hospital of Hefei (Hefei Hospital Affiliated to Anhui Medical University), Hefei, China.