Objectives: Ureteric complications (UCs) following renal transplantation (RT) cause significant morbidity and ureteric stents are employed to bridge the vesico-ureteric anastomosis with a view to preventing these complications.
The purpose of this study was to examine the incidence of UCs and outcomes following RT in both stented (STG) and non-stented groups (NSTG) of RT patients.
Methods: This is a retrospective study of a cohort of 650 consecutive RTs [STG (N=267; 41%) and NSTG (N=383; 59%)] performed over a period of 8 years, where the data were retrieved from a prospectively maintained computerised database and case-notes.
Results: The overall incidence of UCs was 6.5% (42/650), which consisted of ureteric obstruction (UO) in 4.3% (28) and ureteric leak (UL) in 2.2%(14) of patients. The incidence of UO was significantly high in the NSTG compared to the STG (6.3% vs.1.5%; P=0.002). However, the incidence of UL (3.4% vs.1.3%; P=0.1) and post-transplant urinary tract infection (UTI) (44% vs.41%; P=0.57) were not significantly different between the STG and NSTG groups. UO and UL were associated with significantly high incidence of UTI (P=0.001 and 0.01, respectively). All UCs were managed successfully without allograft loss.
Conclusions: Routine stenting of ureteric anastomosis resulted in reduced incidence of UO without concomitant increased risk of UTI.
Written by:
Shrestha BM, Darby CR, Moore RH. Are you the author?
Renal Transplant Unit, University Hospital of Wales, Heath Park, Cardiff, UK.
Reference: Kathmandu Univ Med J (KUMJ). 2006 Oct-Dec;4(16):409-414.
PubMed Abstract
PMID: 24097566
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