The initial abstract dealt with PSA levels and the risk of prostate cancer, noting that men with chronic renal failure and elevated PSA had a slightly increased risk of prostate cancer.
Next, there is growing evidence that levels of Total and Free Testosterone impact the population of men at risk for prostate cancer and can significantly impact both the aggressiveness of a prostate cancer and general health issues, potentially reducing their chances of full recovery from surgery. This abstract, like other previous reports, found an association with low Free and Total Testosterone and aggressive prostate tumors (i.e., lower T levels are associated with predominant grade 4 cancers). Unlike other reports however, this group also noted that men with lower T levels did not enjoy the same general health as men with normal T levels. An interesting finding was that men with low T levels were more likely to have larger prostates, lower hemoglobin and increased BMI. They also noted that the higher the T levels the better general health and a better chance of lower grade cancers.
Also: Impact of total and free testosterone on physiological characteristics of men and aggressiveness of prostate cancer in men undergoing RARP
by Thomas E. Ahlering
Presented by Kirk M. Anderson at the 29th World Congress of Endourology & SWL (WCE) - November 30 - December 3, 2011 - Kyoto International Conference Center - Kyoto, Japan
Reported for UroToday by Thomas E. Ahlering, MD, Professor & Vice Chairman, Department of Urology, University of California-Irvine Medical Center, Irvine, CA
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