Several efforts in recent years have been made to predict urinary continence (UC) recovery after radical prostatectomy. The aim of our study was to investigate the impact of surgical urethral length preservation (SULP) on urinary continence after LARP (laparoscopic-assisted radical prostatectomy). We retrospectively queried our datasets from May 2021 to May 2022. After the application of exclusion criteria, a total of 100 patients who underwent LARP for prostate cancer at our institution were enrolled. Through a sterile ruler inserted by a 12 mm trocar, the length of the membranous urethra spared during LARP was assessed intra-operatively. The baseline and peri- and postoperative data of patients were collected, and UC was defined as 0 or 1 on a safety pad. The median SULP was 20.5 mm (IQR, 14.5-25), and the median intraoperative EBL were 150 mL (IQR, 100-200). The Kaplan-Meier curve showed a significant difference at 20 mm, which was used as the cut-off value for SULP (log-rank test, p < 0.001). Multivariate Cox proportional hazards models showed that SULP and EBL < 250 mL were associated with UC recovery (all p < 0.02). Surgical urethral length preservation seemed to improve early UC recovery after LARP. Further multicentric studies are needed to confirm our findings.
Life (Basel, Switzerland). 2023 Jul 13*** epublish ***
Alberto Ragusa, Aldo Brassetti, Francesco Prata, Andrea Iannuzzi, Pasquale Callè, Francesco Tedesco, Loris Cacciatore, Francesco Esperto, Giuseppe Simone, Roberto Mario Scarpa, Rocco Papalia
Department of Urology, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy., Department of Urology, IRCCS "Regina Elena" National Cancer Institute, 00144 Rome, Italy.